Integrated molecular characterisation of endometrioid ovarian carcinoma identifies opportunities for stratification
نویسندگان
چکیده
منابع مشابه
An integrated clinical-genomics approach identifies a candidate multi-analyte blood test for serous ovarian carcinoma.
PURPOSE Cancer of the ovary confers the worst prognosis among women with gynecologic malignancies, underscoring the need to develop new biomarkers for detection of early disease, particularly those that can be readily monitored in the blood. EXPERIMENTAL DESIGN We developed an algorithm to identify secreted proteins encoded among approximately 22,500 genes on commercial oligonucleotide arrays...
متن کاملIntegrated genomic analyses of ovarian carcinoma
Acatalogue ofmolecular aberrations that cause ovarian cancer is critical for developing and deploying therapies thatwill improve patients’ lives. The Cancer Genome Atlas project has analysed messenger RNA expression, microRNA expression, promoter methylation and DNA copy number in 489 high-grade serous ovarian adenocarcinomas and the DNA sequences of exons from coding genes in 316 of these tumo...
متن کاملIntegrated genomic analyses of ovarian carcinoma
Acatalogue ofmolecular aberrations that cause ovarian cancer is critical for developing and deploying therapies thatwill improve patients’ lives. The Cancer Genome Atlas project has analysed messenger RNA expression, microRNA expression, promoter methylation and DNA copy number in 489 high-grade serous ovarian adenocarcinomas and the DNA sequences of exons from coding genes in 316 of these tumo...
متن کاملIntegrated genomic analyses of ovarian carcinoma
Acatalogue ofmolecular aberrations that cause ovarian cancer is critical for developing and deploying therapies thatwill improve patients’ lives. The Cancer Genome Atlas project has analysed messenger RNA expression, microRNA expression, promoter methylation and DNA copy number in 489 high-grade serous ovarian adenocarcinomas and the DNA sequences of exons from coding genes in 316 of these tumo...
متن کاملIntegrated genomic analyses of ovarian carcinoma
Acatalogue ofmolecular aberrations that cause ovarian cancer is critical for developing and deploying therapies thatwill improve patients’ lives. The Cancer Genome Atlas project has analysed messenger RNA expression, microRNA expression, promoter methylation and DNA copy number in 489 high-grade serous ovarian adenocarcinomas and the DNA sequences of exons from coding genes in 316 of these tumo...
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ژورنال
عنوان ژورنال: npj Precision Oncology
سال: 2021
ISSN: 2397-768X
DOI: 10.1038/s41698-021-00187-y